CEFTRIAXONE & TAZOBACTAM INJECTION

GenericName : CEFTRIAXONE & TAZOBACTAM INJECTION

Brand Name : CEFZON – TZ  Injection

Composition :

Each Vial contains :-

Ceftriaxone Sodium Sterile IP equivalent to

Ceftriaxone Anhydrous      4.0 gm

Tazobactum Sodium Sterile IP equivalent to

Tazobactum                      500 mg

Presentation : 4.5 Gm Vial With 20 ml Water for Injection

Description :

 Ceftriaxone is a third-generation cephalosporin antibiotichaving broad-spectrum activity against Gram-positive and Gram-negativebacteria. This is used to treat serious infections, particularly those causedby susceptible strains of Enterobacteriaceae. Sulbactam is a β-lactamaseinhibitor. It works by interfering with the formation of the bacteria’s cellwall so that the wall ruptures, resulting in the death of the bacteria.Ceftriaxone for injection USP is a sterile, semisynthetic, broad-spectrumcephalosporin antibiotic for intravenous or intramuscular administration.

Tazobactam is a penicillinate sulphone, structurallyrelated to sulbactam. Being a beta- lactamase inhibitor, it is synergistic withmany beta-lactamase-labile drugs such as penicillins and cephalosporins.

Tazobactam inhibits allbeta-lactamases inhibited by clavulanic acid, but, in addition, it also hassome activity against chromosomally-mediated induced (or derepressed) enzymesof Morganella morganii, Citrobacter freundii, Enterobacter cloacae,Serratia marcescens and Pseudomonas aeruginosa.Tazobactam also appears to be a weaker enzyme inducer than other beta-lactamaseinhibitors.

Indications :

Mamary Gland Infection – Mastitis

Urinary Track Infection – Cytitis /Nephritis

Uterine Infection – Endometris

Respiratory Track Infections – Pnemonia/ Bronchopnemonia

Hard Tissue Infections – Oestroarthritis

Preoperative and Postoperative Treatment

Uniquefeatures :

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Dosage & Administration :

For I.M. / I.V. Use only

Treatment& Care : If any particle is visible in the vial after dissolving the contents,please do not use the solution and ask for replacement.

Withdrawl Period :  Milk : 7days  &  Meat : 28 days